2631-2581 2631-2581 S2631-25812022000300014 10.46997/revecuatneurol31300014 Ecuador 00 12 2022 00 12 2022 31 3 14 15 2016 374 2335-44 2004 62 1934-8 2017 58 1955-61 2018 98 776-8 2021 106 208-14 2021 78 1045-6