1390-8596 1390-8596 S1390-85962022000200018 10.17163/lgr.n36.2022.02 Ecuador Ecuador Ecuador Ecuador Ecuador 00 02 2022 00 02 2022 36 2 18 31

2016 2001 2017 2012 2007 2017 2015 2009 2013 2004 2007 2015 2016 Centers for Disease Control and Prevention 2019 Centers for Disease Control and Prevention 2020 2001 2016 2019 2012 2009 2015 2010 FDA 2020 2009 2007 2012 2010 2003 2011 2001 2011 2015 2007 2006 2007 2020 2015 2017 2003 2019 2015 2014 2018 2011 2014 2012 2013 2010 2013 2011 WHO 2016 2016 2013 2019