<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2631-2581</journal-id>
<journal-title><![CDATA[Revista Ecuatoriana de Neurología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Ecuat Neurol]]></abbrev-journal-title>
<issn>2631-2581</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Médica Ecuatoriana de Neurología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2631-25812022000200097</article-id>
<article-id pub-id-type="doi">10.46997/revecuatneurol31200097</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Enfermedad De Wilson: A Propósito De Un Caso Neuropsiquiátrico De Diagnóstico Tardío.]]></article-title>
<article-title xml:lang="en"><![CDATA[Wilson&#8217;s Disease: About A Late-Diagnosed Neuropsychiatric Case.]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Huanco-Condori]]></surname>
<given-names><![CDATA[Jéssica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Tomateo-Torvisco]]></surname>
<given-names><![CDATA[Jorge David]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cruzado]]></surname>
<given-names><![CDATA[Lizardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Peruana Cayetano Heredia Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Peru</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2022</year>
</pub-date>
<volume>31</volume>
<numero>2</numero>
<fpage>97</fpage>
<lpage>102</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.senescyt.gob.ec/scielo.php?script=sci_arttext&amp;pid=S2631-25812022000200097&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.senescyt.gob.ec/scielo.php?script=sci_abstract&amp;pid=S2631-25812022000200097&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.senescyt.gob.ec/scielo.php?script=sci_pdf&amp;pid=S2631-25812022000200097&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN La valoración integral de un caso psiquiátrico obliga a evaluar los síntomas desde una perspectiva abarcadora, sin sesgos, y a sospechar patologías improbables en caso pertinente. Subrayamos esto a partir de un caso de enfermedad de Wilson en que, como es frecuente, el diagnóstico fue tardío. Caso clínico: Mujer de 36 años que desde los 18 años presentó síntomas depresivos y luego psicóticos, y su diagnóstico fue esquizofrenia paranoide. El retraso diagnóstico de tres años conllevó una pobre evolución con discapacidades permanentes. La atribución diagnóstica sesgada acerca del parkinsonismo como secundario a los antipsicóticos enturbió la valoración diagnóstica adecuada. Nuestro caso patentiza la necesidad de una perspectiva neuropsiquiátrica integral en la valoración diagnóstica. En un primer caso de psicosis debe considerarse dentro del diagnóstico diferencial a la enfermedad de Wilson.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT The comprehensive assessment of a psychiatric case requires evaluating the symptoms from a comprehensive perspective, without bias, and suspecting unlikely pathologies where appropriate. We emphasize this from a case of Wilson's disease in which, as is frequent, the diagnosis was late. Clinical case: 36 year-old woman who from the age of 18 presented depressive and later psychotic symptoms, and her diagnosis was paranoid schizophrenia. The three-year diagnostic delay led to a poor evolution with permanent disabilities. The biased diagnostic attribution about parkinsonism as secondary to antipsychotics clouded the adequate diagnostic evaluation. Our case shows the need for a comprehensive neuropsychiatric perspective in the diagnostic evaluation. In a first case of psychosis, Wilson's disease should be considered within the differential diagnosis.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Degeneración hepatolenticular]]></kwd>
<kwd lng="es"><![CDATA[rigidez muscular]]></kwd>
<kwd lng="es"><![CDATA[neuropsiquiatría.]]></kwd>
<kwd lng="en"><![CDATA[Hepatolenticular Degeneration]]></kwd>
<kwd lng="en"><![CDATA[muscle rigidity]]></kwd>
<kwd lng="en"><![CDATA[neuropsychiatry.]]></kwd>
</kwd-group>
</article-meta>
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