Abstract

MEJIA ZAMBRANO, Henry. Eficacia de la terapia con aminoglicósidos en infectados por Klelsiella pneumoniae resistente a carbapenémicos. Rev Eug Esp [online]. 2022, vol.16, n.3, pp.92-105. ISSN 2661-6742.  https://doi.org/10.37135/ee.04.15.10.

The treatment of infections by bacteria resistant to certain pharmacological groups is a topic of great interest for science. Thus, the research had the purpose of systematizing the information about the efficacy of aminoglycosides in patients infected by Carbapenem-Resistant Klebsiella pneumoniae. This systematic review was carried out following the PRISMA protocol. The sources were located from a search made in the databases: PubMed, MEDLINE, and SCOPUS; 11 articles were selected that met the established requirements. A predominance of articles from the United States of America (4/11) and Brazil (3/11) was observed. The overall population was 3,778 patients among the 11 studies included. The use of aminoglycosides was more effective than other pharmacological groups in improving clinical status, reflecting lower mortality values in patients hospitalized for the infection in question.

Keywords : aminoglycoside; Klebsiella pneumoniae; Carbapenem-Resistant Enterobacteriaceae.

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