Abstract

MAURI-FABREGA, Lara. Historical Perspective And Current Scenarios Of The Antiganglioside Syndrome. Rev Ecuat Neurol [online]. 2022, vol.31, n.3, pp.62-68. ISSN 2631-2581.  https://doi.org/10.46997/revecuatneurol31300062.

The antiganglioside syndromes constitute a large clinical spectrum. Its knwolegde has evolved from the classical pure clinical descriptions to a wide development of the immunopathology underlying these processes and its possibilities of treatment. In this work we realize a bibliographical review analyzing its evolution from a historical perspective to date at four levels: clinical, topographic, immunologic, and therapeutic. We analyze critically well-known topographical and immunologic notions that are scarcely integrated in daily clinical practice. We debate about the need of establish a new nomenclature for these syndromes in two levels: clinical and immunologic. Finally, we review the current and under development therapeutic lines.

Keywords : Gangliosides; Immunopathology; Nodopathies; Acute polyneuroradiculopathy; Bickerstaff syndrome; Miller-Fisher syndrome; Guillain-Barré syndrome..

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