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Revista Ecuatoriana de Neurología

On-line version ISSN 2631-2581Print version ISSN 1019-8113


LAMBEA-GIL, Alvaro et al. Merkel Cell Carcinoma In A Patient With Multiple Sclerosis Treated With Fingolimod. Rev Ecuat Neurol [online]. 2021, vol.30, n.1, pp.197-199. ISSN 2631-2581.

Fingolimod is a disease-modifying therapy widely used in Relapsing-Remittent Multiple Sclerosis. It blocks the capacity of lymphocytes to leave the lymph nodes, causing lymphopenia. This increases the risk of infections, but also non-melanocytic skin tumours. We report a case of Merkel cell carcinoma in a patient treated with fingolimod and a review of the literature, which helps to understand the relation between immunosuppression, opportunistic infections and cancer.

Keywords : Cancer; Merkel Cell Carcinoma; Fingolimod; Immunosuppression; Adverse effect; Multiple Sclerosis.

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