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Revista Ecuatoriana de Neurología

On-line version ISSN 2631-2581Print version ISSN 1019-8113


AGUIRRE, Luis E.  and  DE LEON-BENEDETTI, Andres. Perspectives on the pharmacologic management of epilepsy: A comprehensive review. Rev Ecuat Neurol [online]. 2019, vol.28, n.3, pp.59-67. ISSN 2631-2581.


Epilepsy represents the third most common reported neurologic disorder, surpassed only by cerebrovascular accidents and Alzheimer’s disease. Iyt is believed that around 70% to 80% of all convulsive disorders can be successfully controlled with monotherapy alone and an additional 10% to 15% with combination therapy. Around 10% of cases never achieve remission through pharmacological therapy alone.


Through this comprehensive review of the literature describing the current available pharmacologic therapies for the management of epilepsy and their recognized indications, the authors intend to provide an educational tool that could assist the general practitioner to make decisions when selecting a suitable treatment strategy according to a specific clinical scenario (and as guided by their own professional judgment, circumstances and clinical reality)-.


We used a wide variety of medical search engines, articles and abstracts for the purpose of data collection and interpretation.


Through this review the authors managed to present all current and innovative approaches regarding the pharmacologic management of epilepsy encompassing the scope of current knowledge.

Keywords : Epilepsy; Pharmacotherapy; Anticonvulsants; Seizures..

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )