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Revista Ecuatoriana de Neurología

On-line version ISSN 2631-2581Print version ISSN 1019-8113


DIAZ-ROJAS, Camilo A.; ROMERO-LEAL, David S.; QUINTERO, Ana M.  and  ESTRADA-OROZCO, Kelly P.. Apparent diffusion coefficient in brain tissue: values of normality in clinically healthy colombian population. Rev Ecuat Neurol [online]. 2019, vol.28, n.3, pp.25-32. ISSN 2631-2581.


The diffusion sequences in magnetic resonance, including the apparent diffusion coefficient (ADC), represent a fundamental tool for the radiologist in the clinical diagnosis. However, there is no standardization for measurements between normal limits or a range of normal ADC values.


To determine normal ADC values ​​in the brain tissue for the clinical and radiologically healthy population.


Cross-sectional study on retrospective data, ADC values ​​were measured for 21 encephalic regions (frontal gray, parietal and temporal substance, frontal and parietal white matter, caudate nucleus, putamen, thalamus, internal capsule, cerebellar hemispheres bilaterally and bridge of the brainstem) in 90 clinically and radiologically healthy subjects, in two private clinics in Bogotá.


Normal ADC values, in a clinical and radiologically healthy population, in 21 encephalic territories, comparative analysis of the results according to the sex and age of the patients, and correlation between the measurements made by two researchers.


The findings serve as a reference for the Colombian and normal Latin American population, establish a point of comparison for the evaluation of intracranial pathologies, and open the possibility to develop new research projects that seek to determine ADC values ​​in sick population.

Keywords : ADC; neuroimaging; magnetic resonance.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )