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Revista Ecuatoriana de Neurología

On-line version ISSN 2631-2581Print version ISSN 1019-8113


LOPEZ-HERNANDEZ, Samsara  and  RODRIGUEZ-ARIAS, Carlos Alberto. Aquaporins And System Nervous Central. Rev Ecuat Neurol [online]. 2019, vol.28, n.2, pp.75-82. ISSN 2631-2581.

The discovery of aquaporins, which constitute a family of integral membrane proteins, has meant a change with respect to the understanding of water transport in biological membranes. The most important is aquaporin 4 (AQP4) which we will focus on below, although there are two other aquaporins, 1 and 9. These aquaporins are of great importance in the physiology of cell volume control and osmotic control mechanisms of the cells. Also in the control of the flow of glycerol and other solutes. In addition, alterations in its functioning have been related to various diseases of the central nervous system such as neuromyelitis optics, cerebral edema, idiopathic intracranial hypertension or chronic hydrocephalus of the adult among others. A review is made on this topic.

Keywords : Aquaporin 1; Aquaporin 4; Cerebrospinal fluid; System nervous central; Intracranial hypertension..

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