SciELO - Scientific Electronic Library Online

 
vol.27 issue2Familial Tourette Syndrome: Case Report And Review Of LiteratureEndovascular Occlusion Of Aberrant Internal Carotid Artery Causing Tinnitus author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Ecuatoriana de Neurología

On-line version ISSN 2631-2581Print version ISSN 1019-8113

Abstract

HERRAEZ, María Clara; DE VALMASEDA, Martín; AJOY-CHAO, Manuel  and  APARICIO-REINOSO, María Teresa. Neuropsiquiatric Manifestations Of Whipple Disease In An Adolescent: Case Report. Rev Ecuat Neurol [online]. 2018, vol.27, n.2, pp.92-95. ISSN 2631-2581.

Whipple disease (WD) is a rare chronic systemic infection caused by the actinomycete Tropheryma Whipplei. The clinical manifestations are mainly intestinal, although occasionally may present extraintestinal locations (joints, heart, pulmonary, central nervous system ...) , and even the last can be the only symptom.

We present a 15-year-old female patient referred to the psychiatry service, with a diagnosis of depression, with a 6-month evolution with worsening, admission due to autolytic attempt and, at the same time, atypical neurological symptomatology. She is referred to Neurology to rule out organic pathology, including autoimmune pathologies (antiNMDA encephalitis, ...), finding in the study, PCR positive Tropheryma Whipplei, and being diagnosed of Whipple disease with neurological involvement. Antibiotic treatment was performed according to the established guidelines, repeated at the end of the treatment the lumbar puncture, resulting this negative and with clinical neurological improvement as well as psychiatric.

Keywords : Whipple´s disease; Neuropsychiatric symptoms; PCR..

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )