Services on Demand
Journal
Article
Indicators
- Cited by SciELO
- Access statistics
Related links
- Similars in SciELO
Share
Revista Ecuatoriana de Neurología
On-line version ISSN 2631-2581Print version ISSN 1019-8113
Abstract
LARA-GIRON, Juan Carlos et al. Histological findings in familial temporal epilepsy in a Mayan descent family. Rev Ecuat Neurol [online]. 2020, vol.29, n.3, pp.102-106. ISSN 2631-2581. https://doi.org/10.46997/revecuatneurol29300102.
Familial temporal lobe epilepsy is a heterogeneous genetic syndrome, initially recognized in studies with twins. In this condition, many members of a family are affected by psychic or autonomic auras and focal seizures with altered consciousness. We describe two brothers, children of non-blood parents, with different phenotypes of familial temporal lobe epilepsy and drug resistance who were referred to our center for epilepsy and functional neurosurgery. The family, of Mayan descent, has a history of epilepsy in other relatives. Epilepsy surgery was performed on the two brothers while remaining seizure-free today. The histological findings in both cases were consistent with cortical focal dysplasia IIIa. It is the first Latin American report of siblings with evidence of a correlation between familial temporal lobe epilepsy and histological changes suggestive of cortical focal dysplasia IIIa.
Keywords : Familial temporal lobe epilepsy; cortical focal dysplasia; drug resistance.