LARA-GIRON, Juan Carlos et al. Histological findings in familial temporal epilepsy in a Mayan descent family. []. , 29, 3, pp.102-106. ISSN 2631-2581.  https://doi.org/10.46997/revecuatneurol29300102.

Familial temporal lobe epilepsy is a heterogeneous genetic syndrome, initially recognized in studies with twins. In this condition, many members of a family are affected by psychic or autonomic auras and focal seizures with altered consciousness. We describe two brothers, children of non-blood parents, with different phenotypes of familial temporal lobe epilepsy and drug resistance who were referred to our center for epilepsy and functional neurosurgery. The family, of Mayan descent, has a history of epilepsy in other relatives. Epilepsy surgery was performed on the two brothers while remaining seizure-free today. The histological findings in both cases were consistent with cortical focal dysplasia IIIa. It is the first Latin American report of siblings with evidence of a correlation between familial temporal lobe epilepsy and histological changes suggestive of cortical focal dysplasia IIIa.

: Familial temporal lobe epilepsy; cortical focal dysplasia; drug resistance.

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